SetPoint Therapy

SetPoint Therapy is the first and only FDA-approved neuroimmune modulation treatment for rheumatoid arthritis. It uses a small implantable device — about the size of a vitamin tablet — to deliver a brief, 60-second pulse to your vagus nerve once a day. The vagus nerve is a major pathway that helps regulate inflammation throughout your body.

Your immune system and nervous system are closely connected, and the vagus nerve normally helps keep inflammation in check. In rheumatoid arthritis, this natural balance can become disrupted. SetPoint Therapy is designed to activate natural pathways to restore balance and reduce the inflammation driving your RA symptoms, without the immune-compromising side effects.

SetPoint Therapy is intended for adults with rheumatoid arthritis who have not found relief with or cannot tolerate biologics or JAK inhibitors. Our providers might recommend SetPoint Therapy if you’ve tried a biologic or JAK inhibitor without success, or if you’re looking for a different treatment approach.  Our providers are the first in Pennsylvania to offer SetPoint Therapy, reflecting our commitment to giving patients access to the most advanced treatment options available.

“We are proud to be able to offer this ground breaking effective nonmedicinal option for patients with moderate to severe rheumatoid arthritis”